What is CBG?

What is CBG? Potential benefits of CBG

We all know about CBD and THC, the most popular and plentiful cannabinoids that offer a wide range of health benefits. But aside from CBD and THC, there is more to the cannabis and hemp plant. Cannabis/hemp contains over a hundred cannabinoids and more than 400 different compounds; most of these active compounds offer natural health and medical benefits. Here we will talk about one of the most important cannabinoids, CBG, which is often overlooked and responsible for other popular cannabinoids.

What is CBG?

CBG (cannabigerol) is a natural compound found in the cannabis and hemp plant. It is an important cannabinoid and considered the “mother of cannabinoids,” as THC and CBD come from the acidic form of CBG. However, it is not as popular as CBD and THC due to its scarcity in the plant. Still, it is gaining momentum, and many businesses are focusing on its production. A harvested plant may contain only a minor amount of 1% -2% CBG. Though CBG was first discovered in the 1960s, it has started getting real attention in the past few years. The cannabis/hemp plant produces cannabigerolic acid (CBGA), an acidic form of cannabigerol, and the precursor to acid forms of different cannabinoids such as CBC, CBD, and THC. When the plant is fresh, it is rich in CBGA, which later turns into CBDA, THCA, and CBCA over time.

These acidic forms of cannabinoids further go through the process of decarboxylating  to achieve the non-acidic forms of THC, CBD, and CBC. After the plant completes it’s growth cycle, a trivial amount of CBGA remains. Due to the small amount of CBGA left in the plant, CBG production is much lower than THC and CBD, making CBG products more expensive and rare to find.

CBG vs. CBD

Many people still think that CBD and CBG are the same cannabinoids, and “G” in CBG is only a typo. However, now it is clear that both are different cannabinoids found in cannabigerolic acid. Both CBD and CBG share many properties but are still two different compounds and serve different purposes. CBG and CBD have the potential to relieve many ailments and give much needed relief while and are considered to be non-psychoactive. They do not get you “high” and arbitrate THC’s psychoactive effect. CBG can activate CB1 receptors, which means it can reduce psycho activation and counterbalance THC’s intoxicating effects if used after smoking or intaking THC rich cannabis. A significant difference between CBG and CBD is the way they interact with our endocannabinoid system. The ability of CBD to directly interact with the brain receptors is limited, while CBG can directly bind CB1 and CB2 receptors and produces direct effects to the ECS (Endocannabinoid System).

Aside from their therapeutic effects and natural properties, the production and extraction of CBG is harder than CBD due to its trivial amount found in the cannabis plant. CBG’s production is comparatively more expensive and involves a delicate process, which is why most manufacturers focus on the extraction of CBD rather than CBG.

Benefits of CBG

CBG is loaded with an array of health and medical benefits, and many pieces of research are made to find out its potential benefits. Though the research on CBG and its advantages is in its initial phase, the early results still indicate CBG’s potential to treat several health conditions. Following are the possible benefits of CBG:

CBG can relieve pain

The cannabis/hemp plant is famous for its pain-relieving properties, and about 97% of cannabis/hemp users are using it for chronic pain. When it comes to pain relief, it is usually attributed to THC, but some studies of CBG show that both acidic and non-acidic forms can relieve pain even more effectively than CBD and THC.

Anti-inflammatory properties

CBG also contains anti-inflammatory properties and can also help treat IBD (Inflammatory Bowel Disease), reduces inflammation in patients with MS (Multiple Sclerosis), and protects the nerves in Huntington’s Disease. The results of an experimental study also show that CBG can effectively relieve inflammation.

CBG can improve Eye Health

Cannabigerol can reduce intraocular pressure and can also help manage glaucoma. Cannabinoids like CBG can activate the endocannabinoid receptors in our eyes and produce relief for intraocular pressure. Many studies suggest that CBG can facilitate the draining of fluids and reduce intraocular pressure.

Treatment of Cancer

According to the researchers, CBG has shown its ability to block the receptors that promote the cells’ growth that causes cancer. In a study performed on the mice subjects with colorectal cancer, CBG has potentially hindered cancerous cells’ growth and reduced the disease’s progression. The studies show that CBG has promising effects against cancer.

Useful to treat Psoriasis

Psoriasis is a condition where the regular skin development system goes wrong and leads to reddening and skin thickening. CBG can inhibit these effects, and according to research, it can prove beneficial to fight against Psoriasis and prevent its symptoms.

CBG as an anti-depressant

Since CBG interacts with the brain receptors, it also plays its part in emotional regulation. The binding properties of CBG with CB1 and CB2 receptors makes it potent for providing therapeutic effects and alleviate depression. It can be a worthy alternative of THC for those who want to ease depression and anxiety without getting high. CBG controls serotonin and GABA levels in the brain and is proved to be more efficient in hindering the uptake of GABA than CBD and THC.

Useful against Bladder Dysfunction

Besides offering other mental and physical benefits, cannabigerol is also useful in managing bladder dysfunction and helping patients with bladder problems. A study conducted to find the effects of CBDV, THCV, CBD, and CBG on bladder contraction indicates that CBG was the most efficient cannabinoid to inhibit muscle contraction in the bladder. The results suggest that CBG might also prove useful for treating various bladder disorders and their symptoms.

Conclusion

While studies on CBG and its benefits are still insufficient, more studies are needed to determine the overall health and medical benefits. Still, the available information about CBGA and CBG can prove the promising benefits of this cannabinoid and its potential to manage various conditions and symptoms. As people continue to find more about the  benefits of CBG,  manufacturers are adopting ways to breed CBG rich plants for medical purposes. At present, CBG oil and CBG products are not as common as CBD products, but in the coming months, you will see many Fourmile CBG products on the market. If you are suffering from any of the conditions mentioned earlier, you can opt for CBG oil and add it to your health routine but make sure to consult with your health care provider before using any cannabinoid.

References:

https://pubmed.ncbi.nlm.nih.gov/23415610/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998228/

https://pubmed.ncbi.nlm.nih.gov/26197538/

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